Medical Science Liaison/Senior Medical Science Liaison Midwest

Company Information

Albireo is a clinical-stage biopharmaceutical company focused on the development and potential commercialization of novel bile acid modulators to treat orphan paediatric liver diseases and other liver or gastrointestinal diseases and disorders. We have deep expertise in bile acid biology and a pipeline of clinical and nonclinical programs.

Odevixibat is a potent and selective inhibitor of the ileal bile acid transporter (IBAT), sometimes also referred to as the apical sodium dependent bile acid transporter (ASBT), that has minimal systemic exposure at therapeutic doses and acts locally in the gut.

Albireo are developing odevixibat initially to treat patients with PFIC, a rare genetic liver disease, and plan to consider additional development in other paediatric cholestatic liver diseases and disorders in the future. Their Phase 3 program in PFIC includes a single randomized, double-blind, placebo-controlled, multicentre clinical trial and an open-label long-term extension study. The double-blind trial, called PEDFIC1, is underway with data read out anticipated in the Middle of 2020. (June/July).

The U.S. Food and Drug Administration (FDA) has granted to the odevixibat PFIC program or elements of it fast track, rare paediatric disease and orphan drug designations. The European Medicines Agency (EMA) has granted odevixibat orphan designation, as well as access to the PRIority MEdicines (PRIME) scheme for the treatment of PFIC. Its Paediatric Committee has agreed to Albireo's odevixibat Pediatric Investigation Plan for PFIC. Both FDA and EMA also have granted orphan drug designation to odevixibat for the treatment of Alagille syndrome and primary biliary cholangitis. Albireo will commercialise Odevixibat in the US, Europe & Canada and will partner in remaining regions.

Job Description

Job Title:          Medical Science Liaison/Senior Medical Science Liaison

Reports To:       VP and Head of Global Medical Affairs

Location:            Midwest

Position Summary:

The Medical Science Liaison is a field-based scientific and clinical expert who strategically supports Albireo’s medical and scientific objectives. The MSL is responsible for identifying, developing and managing peer-to-peer relationships with a variety of healthcare professionals including pediatric hepatologists, gastroenterologists and surgeons. 

He/she will be accountable to engage in high quality communications regarding the science and clinical applications of portfolio to variety of external stakeholders, as well as obtain important insights about current practice, treatment landscapes, and emerging clinical and scientific data. In addition, the MSL is expected to build strong cross-functional relationships, as well as provide meaningful subject-matter experts, to other colleagues at Albireo, in a fully compliant manner. 

Key Duties and Responsibilities:

  • Establish and maintain scientific relationships with national, regional, and local opinion leaders in addition to other healthcare providers
  • Strong, compliant, scientific support of field commercial colleagues including support of sales and market access team initiatives. Provide on-going training to field commercial personnel, providing up to date information on topics of relevance.
  • Respond to unsolicited requests and engage in meaningful, peer-to-peer scientific
  • Stay informed of medical and scientific developments in the pediatric cholestatic disease space by continuously reviewing literature in the field, monitoring competitor activities, networking with experts and attending relevant conferences
  • Planning and support of medical affairs initiatives and booths at scientific congresses
  • Provide internal stakeholders with feedback and insights from interactions and discussions with HCPs
  • Deliver approved medical/scientific presentations to internal & external stakeholders
  • Facilitation of investigator-initiated trials (ISTs)
  • Collaborate with clinical development to enhance patient enrollment in Albireo sponsored clinical trials with site recommendations and maintaining contact with investigators participating in our ongoing trials as needed
  • Lead the planning and execution of subject matter expert meetings/advisory boards
  • Collaborate with cross functional partners on internal projects and external initiatives
  • Adhere to corporate and healthcare compliance guidance in all activities, including those related to clinical trials, scientific interactions with internal and external groups, and responses to unsolicited requests for medical/scientific information
  • Medical Affairs project support including in house initiatives  


  • Advanced degree (MD, PhD or PharmD) is preferred.
  • Field Medical position within the pharmaceutical industry is preferred. Previous experience in pediatric hepatology or pediatric cholestatic related therapeutic area is strongly preferred.
  • Strong clinical knowledge including pharmacotherapy, treatment guidelines, clinical research processes, medical expert engagement strategies, and FDA promotional guidelines, regulations, and ethical guidelines applied to the pharmaceutical industry is required
  • Strong interpersonal communication and presentation skills are required
  • Ability to manage multiple priorities and manage time efficiently.
  • Minimum of 40% overnight travel may be required.

Albireo Values:
Partnership & Commitment
We believe that people and relationships ultimately determine success. We are committed to achieving excellence in everything we do. We strive to identify, attract and develop the best talent for our business, focusing on execution and teamwork.

Enjoyment & Creativity
We encourage individual creativity but believe that team effort produces the best results. We promote opportunities to contribute, providing a positive environment of curiosity and development. In the rapidly changing world of drug development, we work to anticipate changes and develop innovative approaches to meeting our goals.

Mutual Trust & Respect
We value diversity and strive to provide an inviting and inclusive environment. We seek to inspire trust and respect by taking responsibility for our actions, maintaining high ethical standards and encouraging collaboration and honest and straightforward communication.


Equal Opportunity Employer

Albireo Pharma, Inc. is an equal opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

All applicants should be legally entitled to work for any employer in the U.S.

Note to employment agencies: Please do not forward any agency resumes.  Albireo is not responsible for any fees related to resumes that are unsolicited.